Oncolytic Viruses: The Power of Directed Evolution
نویسندگان
چکیده
منابع مشابه
Oncolytic Viruses: The Power of Directed Evolution
Attempts at developing oncolytic viruses have been primarily based on rational design. However, this approach has been met with limited success. An alternative approach employs directed evolution as a means of producing highly selective and potent anticancer viruses. In this method, diverse viruses are grown under conditions that maximize diversity and then passaged under conditions meant to mi...
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1Genelux Corporation, San Diego Science Center, San Diego, CA 92019, USA 2Department of Radiation Oncology, Rebecca and John Moores Comprehensive Cancer Center, University of California, San Diego, CA 92093, USA 3Department of Biochemistry, University of Wuerzburg, 97074 Wuerzburg, Germany 4Rudolf Virchow Center for Experimental Biomedicine, University of Wuerzburg, 97078 Wuerzburg, Germany 5 I...
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ژورنال
عنوان ژورنال: Advances in Virology
سال: 2012
ISSN: 1687-8639,1687-8647
DOI: 10.1155/2012/586389